Science

Host tissue T cells may have an unexpected role in graft-versus-host disease

Host tissue T cells may have an unexpected role in graft-versus-host disease

A new study has found that skin and intestinal T cells in the recipient survive conditioning regimens and continue to perform their normal functions. Under certain conditions, these T cells can become activated by donor white blood cells and play a previously unappreciated role in acute GVHD.

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