Science

NSD2 enzyme appears to prevent cellular senescence

NSD2 enzyme appears to prevent cellular senescence

Using comprehensive genetic analysis, Kumamoto University researchers have found, for the first time, that the NSD2 enzyme blocks cell aging. Inhibition of NSD2 function in normal cells leads to rapid senescence of cells and the amount of NSD2 in senescent cells is significantly reduced. It is hoped that these findings will help clarify the mechanisms of aging, the development of control methods for maintaining NSD2 functionality, and age-related pathophysiology.

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